Efficacy of polyprenyl phosphates in the experimental genital herpes model

Efficacy of polyprenyl phosphates in the experimental genital herpes model

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An experimental model of the primary genital herpes (herpes simplex read more type 2, HSV-2) in the female guinea pigs was suggested to study the infectious process activity of polyprenyl phosphates (PPP) and PPP+acyclovir (AC) complex treatment.The morphofunctional features of the guinea pig ovaries were studied in the control and experimental groups (the latter were inoculated with PPP and/or AC as a primary infection treatment) at the stage of the recurrent genital herpes aggravation.It was shown that in the case of combined PPP +AC use significant changes in the disease symptoms were observed, as well as a decrease in here the infectious process activity and duration, and positive remote effect on the ovarian morphophysiology.